Academic work is never done in a vaccuum, and I owe thanks to several people whose advice and feedback have been invaluable over the course of the work described in this dissertation. First, and most obviously, I owe a lot to Dr. Dong Xie for serving as my advisor. We haven't always seen eye to eye on what the appropriate priorities of this work should be, and he has been very patient in the face of my grumbling. While this project branched out into something far larger than the mere journal extension to his SIRS paper that he had originally envisioned, the original idea that spawned this line of work was entirely his. Other academic collegues that are deserving of mention here are Dr. Ryan Stutsman, whose advice on techniques for representing tail latency distributions was absolutely critical to the work described in Chapter~\ref{chap:tail-latency}, Dr. Jeff Philips, who collaborated with my advisor on grant writing pertinent to this project, and Dr. Zhuoyue Zhao, who collaborated directly with us on the work that ultimately became Chapter~\ref{chap:framework}. Chapter~\ref{chap:design-space} has been influenced, in part, by conversations with Dr. Niv Dayan. I also owe thanks to several of my fellow PhD students. The fact that this document is even vaguely coherent is due in large part to Julia Custatis's attention to detail. Maxwell Norfolk and Jinyu Liu (as well as Julia) all got to suffer through being used as sounding boards for various assortments of my harebrained ideas. Along those same lines, Dr. Jack Sampson was instrumental to the maintenance of my sanity over these past few years. Thanks everyone. I could have never done this without you.